Avidity Partners Management LP

CIK 0001791827 · Q1 2026

13F Equity AUM

$505.3M

+45.8% QoQ

Positions

+13 QoQ

AUM Rank

#4,292

Top 35%

Skill Alpha (FF)

-6.2%/yr^ns

No Clear Edge

Rank #7,665 · Top 93%

vs S&P -11.0%/yr (unadj.)

Quarters Tracked

~6 years

Portfolio Concentration

Top 5: 68.5%Top 10: 80.4%Top 20: 92.0%

DNTH34.9%

CGON17.3%

ORKA7.4%

CATX5.0%

JBIO3.9%

ELVN3.1%

TEVA2.7%

CNTX2.6%

RGEN1.8%

PVLA1.7%

Others (42)19.6%

HHI (Herfindahl-Hirschman Index) measures portfolio concentration. Low (<1500) = diversified, Moderate (1500-2500), High (>2500) = concentrated bets.

Sector Allocation

Healthcare97.0%

Unclassified2.1%

Other0.9%

Portfolio weight by GICS sector based on latest 13F filing. Sectors below 2% are grouped as “Other.”

Position Sizing

Positions: 52Median: 0.35%Avg: 1.92%

0–0.5%

30(7.0%)

0.5–1%

6(3.8%)

1–3%

10(17.6%)

3–5%

3(12.0%)

5%+

3(59.6%)

Count of positions per weight bucket — (%) = combined portfolio weight

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Portfolio Overlap

Shared: 50Unique: 2vs 20 funds

0.7%Low

Fund positions

7,299

Consensus CUSIPs

Jaccard similarity of this fund’s portfolio vs the consensus of top 20 funds by AUM. Low (<15%) = contrarian, Moderate (15-40%), High (>40%) = follows the crowd.

Most Similar Funds

Top 9 benchmark funds with highest portfolio overlap (Jaccard similarity)

GEODE CAPITAL MANAGEMENT, LLC

1.5%

BlackRock, Inc.

1.2%

MORGAN STANLEY

0.9%

VANGUARD CAPITAL MANAGEMENT LLC

1.3%

STATE STREET CORP

1.3%

BANK OF AMERICA CORP /DE/

0.9%

FMR LLC

1.4%

VANGUARD PORTFOLIO MANAGEMENT LLC

1.4%

JPMORGAN CHASE & CO

0.8%

Jaccard similarity per fund: shared CUSIPs / (fund A + fund B − shared). Higher values indicate more similar portfolios.

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Position Changes This Quarter

New28Increased11Decreased10Exited15

New Positions

VIR1.7%

+950K

AKTIS ONCOLOGY INC1.7%

+469K

HUM1.2%

+25K

DC41.1%

+90K

TENX0.7%

+216K

GILD0.6%

+20K

SATELLOS BIOSCIENCE …0.4%

+388K

PODD0.3%

+10K

CRVS0.3%

+115K

CRL0.3%

+10K

Increased

CATX5.0%

+2.8M(+88%)

IMUX1.5%

+2.0M(+43%)

KPTI0.5%

+329K(+245%)

ELVN3.1%

+260K(+185%)

ORKA7.4%

+100K(+15%)

PVLA1.7%

+51K(+263%)

PHAT0.6%

+43K(+21%)

TEVA2.7%

+33K(+8%)

RGEN1.8%

+28K(+55%)

EHC0.8%

+10K(+33%)

Decreased

CNTX2.6%

-506,588(-9%)

CGON17.3%

-183,751(-12%)

KVUE0.3%

-132,800(-57%)

ACAD0.1%

-93,933(-88%)

BSX0.7%

-54,500(-48%)

CNC0.5%

-49,400(-41%)

GMAB0.3%

-42,000(-46%)

ICLR0.3%

-17,100(-52%)

MDT1.7%

-7,600(-7%)

NTRA0.4%

-2,800(-24%)

Exited

-21,000

-9,520

-41,500

-203,600

-17,000

-6,700

-67,300

-11,600

ABG

-9,400

IM8N

-17,700

Quarter-over-quarter changes compared to prior 13F filing. New = first appearance; Exited = no longer held.

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Holdings

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