Rock Springs Capital Management LP

CIK 0001595725 · Q1 2026

13F Equity AUM

$1.7B

-13.0% QoQ

Positions

100

+2 QoQ

AUM Rank

#1,980

Top 16%

Skill Alpha (FF)

-0.8%/yr^ns

No Clear Edge

Rank #3,425 · Top 42%

vs S&P -6.8%/yr (unadj.)

Quarters Tracked

~12 years

Portfolio Concentration

Top 5: 26.2%Top 10: 40.6%Top 20: 60.3%

RVMD6.9%

LLY5.3%

MDGL5.3%

MIRM4.4%

ARGX4.2%

RYTM3.5%

IM8N3.0%

ASND2.6%

XENE2.6%

TVTX2.6%

Others (90)59.4%

HHI (Herfindahl-Hirschman Index) measures portfolio concentration. Low (<1500) = diversified, Moderate (1500-2500), High (>2500) = concentrated bets.

Sector Allocation

Healthcare97.5%

Unclassified2.2%

Other0.3%

Portfolio weight by GICS sector based on latest 13F filing. Sectors below 2% are grouped as “Other.”

Position Sizing

Positions: 100Median: 0.53%Avg: 1.00%

0–0.5%

48(10.2%)

0.5–1%

19(13.9%)

1–3%

26(43.1%)

3–5%

4(15.2%)

5%+

3(17.6%)

Count of positions per weight bucket — (%) = combined portfolio weight

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Portfolio Overlap

Shared: 99Unique: 1vs 20 funds

1.4%Low

100

Fund positions

7,299

Consensus CUSIPs

Jaccard similarity of this fund’s portfolio vs the consensus of top 20 funds by AUM. Low (<15%) = contrarian, Moderate (15-40%), High (>40%) = follows the crowd.

Most Similar Funds

Top 9 benchmark funds with highest portfolio overlap (Jaccard similarity)

BlackRock, Inc.

2.4%

MORGAN STANLEY

1.8%

GEODE CAPITAL MANAGEMENT, LLC

2.7%

STATE STREET CORP

2.7%

BANK OF AMERICA CORP /DE/

1.9%

FMR LLC

JPMORGAN CHASE & CO

1.8%

VANGUARD CAPITAL MANAGEMENT LLC

2.5%

VANGUARD PORTFOLIO MANAGEMENT LLC

2.9%

Jaccard similarity per fund: shared CUSIPs / (fund A + fund B − shared). Higher values indicate more similar portfolios.

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Position Changes This Quarter

New11Increased37Decreased24Exited9

New Positions

MINIMED GROUP INC0.9%

+1.1M

INDV0.4%

+200K

SYK0.3%

+15K

NVO0.2%

+90K

VKTX0.2%

+96K

CVS0.2%

+40K

IPSC0.2%

+1.3M

DNTH0.1%

+27K

AGILON HEALTH INC0.1%

+260K

ORKA0.0%

+4K

Increased

HTFL0.8%

+295K(+106%)

ERAS1.1%

+152K(+16%)

BSX1.9%

+116K(+29%)

PTCT0.7%

+100K(+161%)

EDA0.3%

+92K(+7%)

OLMA0.1%

+72K(+73%)

BCAX0.6%

+60K(+14%)

DYN1.0%

+59K(+6%)

MIRM4.4%

+49K(+6%)

ATEC0.2%

+48K(+16%)

Decreased

AM60.0%

-1,908,869(-99%)

GOSS0.0%

-1,657,468(-51%)

TVTX2.6%

-732,368(-33%)

CMPX1.0%

-621,894(-16%)

PHR0.3%

-276,200(-32%)

COGT1.4%

-224,875(-26%)

OMDA0.4%

-199,000(-27%)

XBI0.2%

-192,000(-86%)

RVMD6.9%

-125,805(-9%)

CAI0.6%

-124,500(-18%)

Exited

-601,800

-204,878

-213,731

-9,573,000

-152,586

-6,500,000

-208,771

INDIVIOR PLC

-105,100

NUVB/WS

-134,028

Quarter-over-quarter changes compared to prior 13F filing. New = first appearance; Exited = no longer held.

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Holdings

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